how long does ketamine stay in your system

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how long does ketamine stay in your system

Ketamine is administered by injection into a vein (intravenous or IV) or muscle (intramuscular or IM). A ketamine nasal spray has also been recently approved by the FDA for the treatment of patients with treatment-resistant depression.8 At lower doses ketamine produces pain relief and sedation, while at higher dosages the drug produces dissociation and hallucinatory effects. The effects appear within seconds when the drug is given IV, whereas it can take up to 4 minutes for the onset of action when given IM.7

Depending on how it is administered, the effects of ketamine can last anywhere from 5 to 30 minutes. Following administration, ketamine is quickly metabolized by the liver into less active metabolites. Approximately 90% of ketamine is excreted in the urine in the form of metabolites.9 The half-life of ketamine, which is the time it takes for the total amount of drug in the body to be reduced by 50%, is about 2.5 hours in adults and 1 to 2 hours in children.10

From a clinical standpoint it is estimated that a drug is effectively eliminated after 4-5 half-lives, meaning the majority of ketamine should be out of the system of an adult in about 10 to 12.5 hours. Factors such as age, body mass, metabolic rate, drug dosage, and route of administration can affect the duration and elimination of the drug.7

A study published in the International Journal of Legal Medicine found that ketamine can be detected in hair up to 4 months after a single dose.11 Ketamine and its metabolites were also detected in scalp samples collected by a wet cotton swab up to 48 hours after administration of the drug. In a study of urine samples collected from hospitalized children who had received ketamine as an anesthetic, ketamine could be detected in the urine up to 11 days after drug administration and its metabolites could be detected for up to 14 days.12 BK-EBDP ephylone

Ketamine Abuse Treatment Options

Prolonged abuse of ketamine may result in psychological dependence. Chronic users will experience cravings when not taking the drug, making it hard to quit because the body is not used to functioning without it. Ketamine withdrawal symptoms can last for 4-6 days and can include:13

  • Cravings for ketamine
  • Loss of appetite
  • Tiredness
  • Chills
  • Sweating
  • Restlessness
  • Tremors
  • Anxiety
  • Depression
  • Irregular and rapid heartbeat

If you currently use ketamine and find it difficult to quit, know that help and support are available. Please contact a professional rehab facility to discuss your treatment options with an addiction specialist. If you abruptly stop ketamine use you may experience intense cravings and discomfort, so it may be recommended to undergo medically supervised detox where any withdrawal symptoms can be properly managed. Methamphetamine

How do people take it?

Ketamine is used in medicine as an anesthetic for humans and animals.

By snorting it as a powder

Most people who take powder ketamine will snort it. Users often talk of taking a ‘bump’, meaning they snort a small amount of ketamine. In the UK, snorting is the most common way to take ketamine.

By injecting it

People who regularly use ketamine sometimes inject it to get a bigger hit. They usually inject ketamine into a muscle.

By swallowing it as a tablet

Some people swallow it in tablet form, but this is less common.

By bombing

Some people ‘bomb’ it, which is swallowing the powder wrapped in cigarette paper.

The risks of Ketamine

Physical health risks

  • Ketamine is a very powerful anesthetic that can cause serious harm. Taking ketamine can be fatal, particularly if it is mixed with other drugs.
  • Ketamine can increase your heart rate and blood pressure. It can make you confused, agitated, delirious and disconnected from reality.
  • It can make you feel sick, and it can cause damage to your short- and long-term memory.
  • Because of the body’s loss of feelings, paralysis of the muscles and the mind’s loss of touch with reality, you can be left vulnerable to hurting yourself or being hurt by others.
  • Because you don’t feel pain properly when you’ve recently taken ketamine, you can injure yourself and not know you’ve done it.
  • Ketamine can cause serious bladder problems, with the urgent and frequent need to pee. This can be very painful and the pee can be blood-stained. Although stopping using ketamine can help, sometimes the damage can be so serious that the bladder needs surgical repair or even removal.
  • The urinary tract, from the kidneys down to the bladder, can also be affected and incontinence (uncontrolled peeing) may also develop. how long does ketamine stay in your system
  • Abdominal pain, sometimes called ‘K cramps’, have been reported by people who have taken ketamine for a long time.
  • Evidence of liver damage due to regular, heavy ketamine use is emerging. The liver has a range of important functions, such as cleaning your blood and removing toxic substances.

Mental health risks

  • The longer term effects of ketamine use can include flashbacks, memory loss and problems with concentration.
  • Regular use can cause depression and, occasionally, psychotic symptoms such as hallucinations. Ketamine can also make existing mental health problems worse.
  • Interestingly, medical grade ketamine is now being researched as a potential treatment for severe depression, but it is too early to know the results of this research. how long does ketamine stay in your system

What is ketamine cut with?

Street ketamine is usually sold as a white/beige crystalised powder and is sometimes cut with other powders to add weight and improve the dealer’s profits.

It’s impossible to tell whether the ketamine you buy has been cut with other substances by looking at it.

If you need treatment for drug addiction, you’re entitled to NHS care in the same way as anyone else who has a health problem.

With the right help and support, it’s possible for you to get drug free and stay that way.

Where to get help for drugs

A GP is a good place to start. They can discuss your problems with you and get you into treatment.

They may offer you treatment at the practice or refer you to your local drug service.

If you’re not comfortable talking to a GP, you can approach your local drug treatment service yourself.

Visit the Frank website to find local drug treatment services.

If you’re having trouble finding the right sort of help, call the Frank drugs helpline on 0300 123 6600. They can talk you through all your options. 3-fpm

Charity and private drugs treatment

As well as the NHS, there are charities and private drug and alcohol treatment organisations that can help you.

Visit the Adfam website to see a list of useful organisations.

Private drug treatment can be very expensive, but sometimes people get referrals through their local NHS.

Your first appointment

At your first appointment for drug treatment, staff will ask you about your drug use. They’ll also ask about your work, family and housing situation.

You may be asked to provide a sample of urine or saliva.

Staff will talk you through all of your treatment options and agree a treatment plan with you.

They can tell you about local support groups for drug users and their families or carers.

You’ll also be given a keyworker, who will support you throughout your treatment.

What drug treatment involves

Your treatment will depend on your personal circumstances and what you’re addicted to. Your keyworker will work with you to plan the right treatment for you.

Your treatment plan may include a number of different treatments and strategies.

Talking therapies

Talking therapies, such as CBT, help you to see how your thoughts and feelings affect your behaviour.

Treatment with medicines

If you’re dependent on heroin or another opioid, you may be offered a substitute drug, such as methadone.

This means you can get on with your treatment without having to worry about withdrawing or buying street drugs.

Detoxification (detox)

This is for people who want to stop taking opioids like heroin completely. It helps you to cope with the withdrawal symptoms.


Some people find support groups like Narcotics Anonymous helpful. Your keyworker can tell you where your nearest group is.

Reducing harm

Staff at your local drug service will help reduce the risks associated with your drug-taking. For example, you may be offered testing and treatment for hepatitis or HIV.

Where you’ll have your treatment

You may have your treatment while living at home or as a hospital inpatient.

If your drug-related problems are severe or complicated, you may be referred to a residential rehabilitation service.

For more information about residential rehabilitation, or to find a rehab near you, visit rehabonline.

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